If you’re looking to bet on the 49ers-Packers game and need to do some last-minute research, you’re in luck! We’ve put together this handy betting guide, which includes the point spread, moneyline and over-under, as well as the information you’ll need to make the smartest bet.

The game kicks off at 8:20 p.m. ET and can be seen on Fox and the NFL Network. The weather forecast for Santa Clara tonight is calling for a 61-degree temperature at kickoff, clear skies and winds around 5 mph so weather will not be a factor.

The 49ers will be seriously shorthanded and potentially ill-prepared on Thursday night. The organization closed its facility on Wednesday after wide receiver Kendrick Bourne tested positive for COVID-19. Three other players – Brandon Aiyuk (out), Trent Williams (out) and Deebo Samuel (out) – were added to the COVID-19/reserve list. San Francisco’s offense is also ravaged by injury, and the 49ers will be missing starting QB Jimmy Garoppolo, superstar tight end George Kittle, and a trio of running backs (Raheem Mostert, Tevin Coleman and Jeff Wilson Jr.).

The Packers (5-2), meanwhile, go on the road after a disappointing home loss to a  1-win Vikings team, in which they allowed Dalvin Cook to score four touchdowns. They still control the NFC North and are heavy favorites in the division, given the state of the Bears.

The lines, courtesy of BetMGM

Point spread: Packers -7.5
Money line: Packers -358 / 49ers +280
Over-under: 47.5

What you need to know:

According to ESPN’s FPI – which seems to not have updated with all of the 49ers’ inactives – San Francisco has a 59.9% chance to win, and the Packers have a 39.8% chance to win. Those numbers should probably be flipped.

According to Action Network’s public betting info, 63% of bets and 78% of money is on the Packers -7.5. Action on the total is dead-even, with 50% of bets on over 48.5, and 59% of money on the over.

Advice

We went 2-2 last week on Thursday night, but this week has some better lines to bet on.

There’s some extra value in Packers -7.5 given the breadth of the 49ers’ issues in Week 9. I’d feel comfortable betting them up to -9.5.

I would advise staying away from a straight bet on the total this week. With so many of San Francisco’s offensive weapons inactive, it’s impossible to predict how many points we’ll see the 49ers score. This could be a blowout type of game where the 49ers score 3 or 7 points – but at the same time, the Packers didn’t force a Vikings punt until the 4th quarter on Sunday, and it’s difficult to project how practice squad receivers will perform.

We’ve continually seen Thursday night games produce low-scoring results, so I do like a 6-point teaser on Packers -1.5, under 53.5.

Prop bets

49ers team total under 20.5 (-143)

Alright, I know I said the 49ers offense will be unpredictable – but there is absolutely no way Nick Mullens – a capable backup – should be able to score 21 with the group they’ll have available.

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